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Search Result

Search Results for " rip-1 kinase inhibitor 1 "

12

Compounds

Cat No. Product Name Synonyms Targets
T9305 Necroptosis-IN-1 RIP kinase
Necroptosis-IN-1 is a potent necroptosis inhibitor of RIPK1. It is an analog of Necrostatin-1.
T1847 Necrostatin-1 Nec-1,Necrostatin 1 Indoleamine 2,3-Dioxygenase (IDO) , Ferroptosis , Autophagy , RIP kinase
Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity. Necrostatin-1 inhibits TNF-α-induced necrotic apoptosis. Necrostatin-1 also inhibits IDO.
T5401 GSK2983559 active metabolite GSK2983559,RIPK2 inhibitor 1,RIPK2-IN-1 RIP kinase
GSK2983559 active metabolite (RIPK2-IN-1) is a potent, selective receptor-interacting protein-2 (RIP2) kinase inhibitor.
T9079 Apostatin-1 Apt-1 Others
Apostatin-1 (Apt-1) is a novel TRADD inhibitor. Apostatin-1 can bind to a pocket on the N-terminal TRAF2 binding domain of TRADD.
T12493 PK68 Others , RIP kinase
PK68 is an effective and selective inhibitor of type II receptor-interacting kinase 1 (RIPK1, IC50 = 90 nM). PK68 can be used for research on the treatment of inflammatory disorders and cancer metastasis.
T11492 GSK2983559 free acid Others , RIP kinase
GSK2983559 free acid is an effective and selective inhibitor of receptor-interacting protein 2 (RIP2). GSK2983559 free acid shows excellent activity in blocking many proinflammatory cytokine responses in human inflammato...
T12731 RIPK1-IN-7 RIP kinase
RIPK1-IN-7 is a potent and selective inhibitor of RIPK1(Kd of 4 nM and an enzymatic IC50 of 11 nM),andexhibits excellent antimetastasis activity in the experimental B16 melanoma lung metastasis model.
T40187 GNF2133 DYRK
GNF2133 is an effective and selective inhibitor of DYRK1A with IC50s of 6.2 nM. GNF2133 can be used in studies about type 1 diabetes.
T12727 RIP2 kinase inhibitor 1 Others
RIP2 kinase inhibitor 1 is a potent and selective receptor interacting inhibitor of protein 2 (RIP2) kinase(RIP2 FP with an IC50 of 0.03 μM ),and is used for autoinflammatory disorders.
T12725 RIP1 kinase inhibitor 1 Others
RIP1 kinase inhibitor 1 is an orally available and brain-penetrating inhibitor of RIP1 kinase with pKi of 9.04.
T7504 Necrostatin 2 racemate Necrostatin-2 racemate RIP kinase
Necrostatin 2 racemate (Necrostatin-2 racemate) is an potent and specific inhibitor of RIPK1.
T36243 PROTAC RIPK degrader-6
PROTAC RIPK degrader-6 (example 1) is a PROTAC designed for the targeted degradation of RIP Kinase, featuring a RIP2 kinase inhibitor connected through a linker to a cereblon binder[1].
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